Menlo Ventures Reports Surge in Healthcare AI Usage and Spending

Major healthcare providers like Kaiser Permanente and Mayo Clinic are investing heavily in AI
Nov. 24, 2025
2 min read

Key Highlights

  • 22 percent of healthcare organizations are now using domain-specific AI tools, a sharp increase from previous years.
  • AI spending in healthcare hit $1.4 billion in 2024, nearly tripling from 2023.
  • Key categories driving growth include ambient clinical documentation and coding automation, with patient engagement and prior authorization also rapidly expanding.
  • Leading providers like Kaiser Permanente and Mayo Clinic are deploying AI solutions across hundreds of facilities, focusing on operational efficiency and improved patient outcomes.
  • The industry is experiencing a transformative shift, with AI adoption accelerating faster than the broader economy and reshaping healthcare delivery.

In October, venture capital firm Menlo Ventures published a report on AI adoption in healthcare. The research indicated that 22 percent of healthcare organizations are using domain-specific AI tools, a sevenfold increase from 2024 and a tenfold increase from 2023. Health systems have the highest adoption rate at 27 percent, with outpatient providers at 18 percent and payers at 14 percent.

According to Menlo Ventures, the $4.9 trillion healthcare industry, which accounts for one-fifth of the U.S. economy but only 12 percent of software spending, is now adopting AI at more than twice the rate of the overall economy (2.2x). “Healthcare AI spending hit $1.4 billion this year, nearly tripling 2024’s investment.”

Large-scale investments and adoption by leading players show how the industry has transformed through AI over the past 12 months:

  • Kaiser Permanente deployed Abridge’s ambient documentation solution across 40 hospitals and 600+ medical offices.
  • Advocate Health evaluated over 225 AI solutions to select 40 use cases to go live with. The initiatives are projected to reduce documentation time by more than 50 percent, while automating prior authorizations, referrals, and coding workflows.
  • Mayo Clinic is investing more than $1 billion in AI over the next few years across more than 200 projects that go beyond administrative automation to include diagnostics and patient care.
  • SimonMed has scaled its partnerships from co-building with fewer than 10 vendors to piloting solutions from more than 50, including AI systems for intake, ambient scribing, and revenue cycle management.
  • Grow Therapy is building an AI care companion that bridges in-session therapy with 24/7 support and pioneering continuous measurement through voice and language analysis to replace static assessment tools.

According to the research, two categories that address urgent operational pain points and deliver measurable ROI are ambient clinical documentation ($600 million) and coding and billing automation ($450 million). Other fast-growing categories include patient engagement (+20x year over year) and prior authorization (+10x year over year).

The report data is based on comprehensive surveys of more than 700 healthcare executives across the U.S.

About the Author

Pietje Kobus

Pietje Kobus

Pietje Kobus has an international background and experience in content management and editing. She studied journalism in the Netherlands and Communications and Creative Nonfiction in the U.S. Pietje joined Healthcare Innovation in January 2024.

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