NIH Pragmatic Trials Collaboratory Adds Implementation, Equity Working Groups

Nov. 2, 2022
Implementation Science Core will study methods and strategies to promote the uptake of interventions that have proven effective in routine practice, with the aim of improving population health

The NIH Pragmatic Trials Collaboratory has added two new Core Working Groups that will be focused on implementation science and health equity.

The Collaboratory supports the design and rapid execution of pragmatic clinical trial demonstration projects that address questions of major public health importance and engage healthcare delivery systems in research partnerships. Other Core Working Groups include Biostatistics and Study Design, Electronic Health Records, Ethics and Regulatory, Health Care Systems Interactions, and Patient-Centered Outcomes.

The Implementation Science Core will provide technical support and pragmatic trial expertise for NIH Collaboratory Demonstration Projects with a specific focus on innovative dissemination and implementation science approaches. The Core will study methods and strategies to promote the uptake of interventions that have proven effective in routine practice, with the aim of improving population health.

The Implementation Science Core will be co-led by Devon Check and Hayden Bosworth. Devon Check, Ph.D., is a health services and implementation researcher and assistant professor, in the Department of Population Health Sciences at Duke University. Hayden Bosworth, Ph.D., is a health services and implementation researcher and deputy director for the Center for Health Services Research in Primary Care at the Durham VA Medical Center as well as professor in the Department of Population Health Sciences and Professor of Medicine, Psychiatry, and Nursing at Duke University Medical Center.

The Health Equity Core will provide leadership and guidance that will help the NIH Pragmatic Trials Collaboratory, its trials and investigators be more equitable in research. The Core’s work includes supporting pragmatic trials to address social and structural drivers of inequities, implement patient and community engagement strategies, promote the inclusion and mentorship of historically underrepresented scientists, and develop culturally and contextually aligned research and translation strategies that overcome bias and resonate with patients and communities.

The Health Equity Core will be led by Rosa Gonzalez-Guarda, Ph.D., M.P.H., R.N., an associate professor of nursing at Duke University, faculty lead for the Population Health Research Area of Excellence at Duke’s Center for Nursing Research, and co-director of the Community Engagement Core for Duke Clinical Translational Science Institute.

“By launching these two new Core Working Groups, the NIH Pragmatic Trials Collaboratory is reaffirming its commitment to generating knowledge that supports equitable pragmatic research to improve healthcare for all,” said Adrian Hernandez, M.D., co-principal investigator of the NIH Pragmatic Trials Coordinating Center, in a statement. “Through their work in the areas of implementation science and health equity, the new Cores can help uncover how best to implement improved clinical practices so the benefits reach at-risk and traditionally underserved populations.”

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